We need your consent to use the individual data so that you can see information about your interests, among other things. Click "OK" to give your consent.
Standard Guide for Performance of the Chinese Hamster Ovary Cell/Hypoxanthine Guanine Phosphoribosyl Transferase Gene Mutation Assay
STANDARD published on 1.1.1996
Designation standards: ASTM E1262-88(1996)
Note: WITHDRAWN
Publication date standards: 1.1.1996
SKU: NS-41059
The number of pages: 5
Approximate weight : 15 g (0.03 lbs)
Country: American technical standard
Category: Technical standards ASTM
Keywords:
Assay, Bioassay, Biological data analysis, Cell culture, Chemicals, Chinese hamster, Genetic examination, Hamsters, Hypoxanthine guanine phosphoribosyl transferase, Industrial materials/applications-metals/alloys, Toxicity/toxicology, performance of the Chinese hamster ovary cell/hypoxanthine guanine, phosphoribosyl transferase gene mutation assay, guide, ICS Number Code 07.080 (Biology. Botany. Zoology)
1. Scope |
1.1 This guide highlights some of the more relevant biological concepts as they are currently understood, and summarizes the critical technical aspects for acceptable bioassay performances as they currently are perceived and practiced. The Chinese hamster ovary cell/hypoxanthine guanine phosphoribosyl transferase (CHO/HGPRT) assay (1) has been widely applied to the toxicological evaluation of industrial and environmental chemicals. 1.2 This guide concentrates on the practical aspects of cell culture, mutagenesis procedures, data analysis, quality control, and testing strategy. The suggested approach represents a consensus of the panel members for the performance of the assay. It is to be understood, however, that these are merely general guidelines and are not to be followed without the use of sound scientific judgement. Users of the assay should evaluate their approach based on the properties of the substances to be tested and the questions to be answered. 1.3 Deviation from the guidelines based on sound scientific judgement should by no means invalidate the results obtained. 1.4 This standard may involve hazardous materials, operations, and equipment. This standard does not purport to address all of the safety problems associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use. |
Do you want to make sure you use only the valid technical standards?
We can offer you a solution which will provide you a monthly overview concerning the updating of standards which you use.
Would you like to know more? Look at this page.
Latest update: 2024-08-30 (Number of items: 2 345 304)
© Copyright 2024 NORMSERVIS s.r.o.