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Standard Test Method for Measurement of Airborne Metal Oxide Nanoparticle Surface Area Concentration in Inhalation Exposure Chambers using Krypton Gas Adsorption
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STANDARD published on 1.10.2018
Designation standards: ASTM E2864-18
Note: WITHDRAWN
Publication date standards: 1.10.2018
SKU: NS-900621
The number of pages: 6
Approximate weight : 18 g (0.04 lbs)
Country: American technical standard
Category: Technical standards ASTM
Keywords:
BET surface area, gas sorption analysis, inhalation exposure, krypton, metal and metal oxide nanoparticles, multipoint surface area, outgassing, physical adsorption, surface area,, ICS Number Code 07.120 (Nanotechnologies),49.025.05 (Ferrous alloys in general)
Significance and Use | ||||||||||||
5.1 A tiered strategy for characterization of nanoparticle properties is necessary to draw meaningful conclusions concerning dose-response relationships observed during inhalation toxicology experiments. This tiered strategy includes characterization of nanoparticles as produced (that is, measured as the bulk material sold by the supplier) and 5.2 Test Methods B922 and C1274 and ISO 9277 and ISO 18757 exist for determination of the as produced surface area of bulk metal and metal oxide powders. During the delivery of nanoparticles in inhalation exposure chambers, the material properties may undergo change and therefore have properties that differ from the material as produced. This test method describes the determination of the 1.1 This test method covers determination of surface area of airborne metal oxide nanoparticles in inhalation exposure chambers for inhalation toxicology studies. Surface area may be measured by gas adsorption methods using adsorbates such as nitrogen, krypton, and argon (Brunauer et al. (1),2 Anderson 1.2 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. State all numerical values in terms of SI units unless specific instrumentation software reports surface area using alternate units. 1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use. 1.4 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee. |
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